AAPC 2026-2027 Guidelines Aligned | Full 12-Module Breakdown

CPC Exam Syllabus: Full 12-Module Content Blueprint

Every surgical series, evaluation and management guideline, diagnostic convention, and compliance regulation mapped directly to the official AAPC 100-question testing domains.

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12
Curriculum Modules
40+
Training Hours
600+
Practice Questions
100%
AAPC Domain Mapped
Quick Jump to Module:
Mod 1 Mod 2 Mod 3 Mod 4 Mod 5 Mod 6 Mod 7 Mod 8 Mod 9 Mod 10 Mod 11 Mod 12
Module 01 • Duration: 3.5 Hours
8-10 Questions (8-10% Exam Weight)

Medical Terminology, Human Anatomy & Pathophysiology

Clinical Learning Objective

Master medical word roots, surgical prefixes, anatomical directional planes, and systemic pathologies required to parse complex physician operative reports rapidly.

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Core Topics & Code Sets

  • Word roots, combining forms, prefixes, and surgical suffixes (-ectomy, -ostomy, -otomy, -plasty)
  • Major organ systems: Integumentary, Musculoskeletal, Cardiovascular, Respiratory, Digestive, Nervous, Genitourinary
  • Anatomical directional terminology: Anterior/Posterior, Proximal/Distal, Medial/Lateral, Superior/Inferior
  • Cellular biology, neoplastic transformations, benign versus malignant behavior, and chronic systemic pathologies
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Auditing Skills Built

Rapid operative report parsing and immediate surgical approach identification without consulting reference tables.

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Practice & Testing Component

50-question flash drill targeting anatomical structures, pathological terms, and high-frequency surgical prefixes.

Module 02 • Duration: 4.0 Hours
10-12 Questions (10-12% Exam Weight)

ICD-10-CM Official Coding Guidelines & Conventions

Clinical Learning Objective

Apply CDC and CMS Official Guidelines for Coding and Reporting across all 22 chapters of the ICD-10-CM tabular list and alphabetic index.

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Core Topics & Code Sets

  • General conventions: Excludes1 versus Excludes2 notes, Code Also, Code First, and In Diseases Classified Elsewhere
  • Infectious diseases (Chapter 1), Neoplasms (Chapter 2), and Endocrine/Diabetes combination rules (Chapter 4)
  • Circulatory and Hypertensive organ disease relationships (Chapter 9: I10, I11, I12, I13 combinations)
  • Trauma and poisoning 7th character extensions: A (initial), D (subsequent), and S (sequela) across Chapters 19 and 20
  • Social determinants of health (Z55-Z65) and clinical status/screening encounters (Chapter 21)
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Auditing Skills Built

Diagnostic sequencing rules, manifestation pairing, causal assumptions, and lateralized fracture coding.

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Practice & Testing Component

25 case-based diagnostic clinical chart scenarios requiring precise guideline citation and sequencing.

Module 03 • Duration: 3.5 Hours
6-8 Questions (6-8% Exam Weight)

Integumentary System Surgery (10000 Series)

Clinical Learning Objective

Accurately code skin, subcutaneous tissue, and accessory structure procedures with precise calculation of excised margins and layered wound repairs.

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Core Topics & Code Sets

  • Incision and drainage (I&D) simple versus complex (10060-10061, 10080-10081)
  • Benign (11400-11446) versus malignant (11600-11646) lesion excision sizing calculations including surgical margins
  • Wound repairs: Simple (12001-12018), Intermediate (12031-12057), and Complex (13100-13153) grouping and summing rules
  • Adjacent tissue transfers/rearrangements (14000-14350) and full/split thickness skin replacement autografts (15002-15278)
  • Destruction of premalignant/malignant lesions and Mohs micrographic surgery (17311-17315) stage/block allocation
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Auditing Skills Built

Excised diameter plus margin math formulas, repair bundling exclusions, and Mohs surgical stage differentiation.

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Practice & Testing Component

20 complex surgical operative report exercises covering simultaneous lesion excision with intermediate layered repair.

Module 04 • Duration: 4.0 Hours
6-8 Questions (6-8% Exam Weight)

Musculoskeletal System Surgery (20000 Series)

Clinical Learning Objective

Differentiate open, closed, and percutaneous fracture treatments, arthroscopic versus open joint interventions, and complex spinal instrumentations.

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Core Topics & Code Sets

  • General musculoskeletal rules: Deep versus superficial biopsies, muscle wound exploration, and foreign body extraction
  • Fracture care: Closed treatment with/without manipulation, open treatment with internal fixation (ORIF), and external fixation
  • Spine surgery: Arthrodesis approaches (anterior, posterior, lateral), spinal instrumentation add-on codes, and bone grafts
  • Endoscopy/arthroscopy rules (29800-29999) versus open arthrotomy procedures and diagnostic-to-surgical conversions
  • Application of casts, strapping, and splints (29000-29750) initial versus replacement guidelines
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Auditing Skills Built

Fracture terminology analysis, approach-based code selection, and add-on spinal instrumentation pairing.

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Practice & Testing Component

25 orthopedic and trauma operative report coding challenges covering fracture reduction and spinal arthrodesis.

Module 05 • Duration: 4.5 Hours
8-10 Questions (8-10% Exam Weight)

Cardiovascular & Respiratory Systems (30000 Series)

Clinical Learning Objective

Navigate thoracic, pulmonary, and vascular procedures including selective arterial catheterization hierarchies and coronary bypass graft combinations.

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Core Topics & Code Sets

  • Endoscopic sinus surgery and diagnostic versus therapeutic bronchoscopy (31622-31654)
  • Coronary artery bypass grafting (CABG): Combined venous and arterial graft rules (33510-33536)
  • Pacemakers and implantable defibrillators: Insertion, revision, and lead replacement coding
  • Vascular catheterization: First, second, and third-order branch hierarchy and non-selective access
  • Central venous access devices: Tunneled versus non-tunneled, subcutaneous port versus pump, insertion by patient age
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Auditing Skills Built

Vascular branching map navigation, order tracking, and CABG arterial/venous combination code assignment.

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Practice & Testing Component

20 cardiovascular and pulmonary case studies with step-by-step vascular order hierarchy tracking.

Module 06 • Duration: 3.5 Hours
6-8 Questions (6-8% Exam Weight)

Digestive System Surgery (40000 Series)

Clinical Learning Objective

Accurately code upper and lower gastrointestinal endoscopies, multi-technique polyp removals, hernia repairs, and hepatobiliary resections.

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Core Topics & Code Sets

  • Upper GI endoscopy (EGD) diagnostic versus therapeutic (biopsy, dilation, stent placement, control of bleeding)
  • Colonoscopy rules: Scope advancement to cecum, hot biopsy versus snare versus cold snare/forceps unbundling rules (45378-45398)
  • Hernia repair coding: Inguinal, femoral, umbilical, incisional/ventral, reducible versus incarcerated/strangulated
  • Laparoscopic versus open cholecystectomy with concurrent intraoperative cholangiography
  • Bariatric surgeries: Laparoscopic sleeve gastrectomy, gastric bypass Roux-en-Y, and revision interventions
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Auditing Skills Built

Multiple polyp removal technique differentiation, diagnostic-to-surgical endoscopy crosswalks, and hernia categorization.

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Practice & Testing Component

20 gastroenterology operative records with multiple polyp removals and concomitant hernia repair.

Module 07 • Duration: 3.5 Hours
6-8 Questions (6-8% Exam Weight)

Urinary, Male & Female Genital Systems (50000 Series)

Clinical Learning Objective

Code urologic endoscopies, prostatectomies, obstetric global packages, and gynecological surgical interventions.

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Core Topics & Code Sets

  • Cystourethroscopy rules: Fulguration, biopsy, ureteral catheterization, and TURBT tumor size measurement tiers
  • Male genital: Prostate biopsy (needle versus needle core), transurethral resection (TURP), and vasectomy
  • Female genital: Colposcopy, cervical conization/LEEP, and hysterectomy coding by approach (vaginal, abdominal, laparoscopic)
  • Maternity care and delivery: Global package (59400, 59510, 59610) versus split antepartum, delivery, and postpartum components
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Auditing Skills Built

Global obstetric package component splitting and TURBT lesion size classification.

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Practice & Testing Component

20 urology and obstetrics case reports with split maternity billing scenarios.

Module 08 • Duration: 3.0 Hours
5-7 Questions (5-7% Exam Weight)

Nervous, Ophthalmic & Auditory Systems (60000 Series)

Clinical Learning Objective

Code central and peripheral nervous system interventions, ophthalmic surgeries, and auditory procedures.

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Core Topics & Code Sets

  • Spinal puncture, epidural and subarachnoid injections, and transforaminal nerve blocks with image guidance
  • Neurostimulator pulse generator and lead insertion/programming (63650-63688)
  • Eye and ocular adnexa: Cataract extraction with intraocular lens (66982 versus 66984 complex versus standard)
  • Strabismus surgery and retinal detachment repair (cryotherapy, vitrectomy, scleral buckle)
  • Auditory: Myringotomy, tympanostomy tube insertion (local versus general anesthesia), and tympanoplasty
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Auditing Skills Built

Image guidance unbundling rules for spinal injections and complex versus standard cataract criteria.

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Practice & Testing Component

15 neurology and ophthalmology surgical operative records.

Module 09 • Duration: 5.0 Hours
10-12 Questions (10-12% Exam Weight)

Evaluation and Management (E/M) Mastery

Clinical Learning Objective

Flawlessly score office visits, hospital admissions, consultations, and emergency department encounters using 2026 MDM and Time guidelines.

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Core Topics & Code Sets

  • The 3 Medical Decision Making elements: Number/complexity of problems, amount/complexity of data, and risk of complications
  • Office and other outpatient visits (99202-99215) new versus established patient criteria
  • Total physician time calculation rules: Countable versus non-countable activities on the date of encounter
  • Hospital inpatient and observation care services (99221-99223, 99231-99233, 99238-99239)
  • Emergency department services (99281-99285), critical care (99291-99292), and nursing facility services
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Auditing Skills Built

Rapid 2-out-of-3 MDM level determination and time threshold calculation.

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Practice & Testing Component

30 comprehensive E/M clinical charts with full MDM scoring worksheets.

Module 10 • Duration: 3.5 Hours
8-10 Questions (8-10% Exam Weight)

Anesthesia, Radiology & Pathology/Laboratory

Clinical Learning Objective

Calculate anesthesia reimbursement units, apply modifier 26/TC to radiology, and prevent lab panel unbundling.

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Core Topics & Code Sets

  • Anesthesia formula: (Base Units + Time Units + Qualifying Circumstances) x Conversion Factor + Physical Status (P1-P6)
  • Radiology: Diagnostic X-ray view counting, CT and MRI with/without contrast coding rules
  • Interventional radiology: Complete component coding (surgical code + radiological supervision and interpretation)
  • Pathology and Laboratory: Automated organ/disease panels (80048, 80053, 80076) unbundling prohibitions
  • Surgical pathology levels (88300-88309) specimen identification rules
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Auditing Skills Built

Anesthesia unit calculation and radiological supervision/interpretation modifier usage.

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Practice & Testing Component

20 anesthesia and interventional radiology multi-code clinical cases.

Module 11 • Duration: 3.5 Hours
8-10 Questions (8-10% Exam Weight)

HCPCS Level II National Codes & CPT Modifiers

Clinical Learning Objective

Master national supply/medication coding and select correct CPT modifiers to overcome NCCI edits and describe procedural alterations.

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Core Topics & Code Sets

  • HCPCS Level II letter classifications: J-codes (drugs), A-codes (medical supplies), E-codes (DME), G-codes (CMS temporary)
  • DMEPOS coding, dosage calculation units for chemotherapy and biologic injections
  • Evaluation and Management modifiers: Modifier 24 (unrelated E/M during global period), Modifier 25 (significant separate E/M)
  • Procedural unbundling modifiers: Modifier 59 versus Medicare X{EPSU} subsets (XE, XP, XS, XU)
  • Surgical modifier nuances: Modifier 22 (increased services), 50 (bilateral), 51 (multiple), 52 (reduced), 53 (discontinued)
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Auditing Skills Built

Medication unit math and NCCI edit modifier justification.

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Practice & Testing Component

25 modifier application case scenarios with correct modifier selection.

Module 12 • Duration: 3.0 Hours
6-8 Questions (6-8% Exam Weight)

Regulatory Compliance, NCCI Edits & Exam Day Mastery

Clinical Learning Objective

Understand healthcare compliance laws, master NCCI PTP/MUE edit tables, and execute a 240-minute test pacing strategy.

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Core Topics & Code Sets

  • HIPAA Privacy, Security, and Breach Notification rules: Protected Health Information (PHI) definition
  • Healthcare fraud and abuse statutes: False Claims Act, Anti-Kickback Statute (AKS), and Stark Law physician self-referral
  • OIG Work Plan, compliance program elements, and Advance Beneficiary Notice (ABN) rules
  • CMS National Correct Coding Initiative (NCCI): Procedure-to-Procedure (PTP) edits and Medically Unlikely Edits (MUE)
  • The 240-Minute Exam Blueprint: 3-pass question triage strategy, book marking conventions, and speed algorithms
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Auditing Skills Built

NCCI column 1/column 2 edit navigation and high-speed exam question elimination.

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Practice & Testing Component

Final 100-Question Comprehensive Timed AAPC CPC Mock Exam with full analytics.

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