Chapter 3
Range: D50-D89
FY2027 Dataset
ICD-10-CM Chapter 3: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50-D89)
Anemias, coagulation defects, purpura, and immune disorders.
Key Diagnosis Codes in Chapter 3
Verified against active FY2027 CDC NCHS code tables.
Showing active FY2027 codes
| Code | Official Descriptor | Status | Action |
|---|---|---|---|
| D50.0 |
Iron deficiency anemia secondary to blood loss (chronic)
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|
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| D50.1 |
Sideropenic dysphagia
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| D50.8 |
Other iron deficiency anemias
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|
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| D50.9 |
Iron deficiency anemia, unspecified
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|
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| D51.0 |
Vitamin B12 defic anemia due to intrinsic factor deficiency
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|
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| D51.1 |
Vit B12 defic anemia d/t slctv vit B12 malabsorp w protein
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|
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| D51.2 |
Transcobalamin II deficiency
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| D51.3 |
Other dietary vitamin B12 deficiency anemia
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|
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| D51.8 |
Other vitamin B12 deficiency anemias
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|
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| D51.9 |
Vitamin B12 deficiency anemia, unspecified
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|
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| D52.0 |
Dietary folate deficiency anemia
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|
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| D52.1 |
Drug-induced folate deficiency anemia
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|
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| D52.8 |
Other folate deficiency anemias
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|
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| D52.9 |
Folate deficiency anemia, unspecified
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| D53.0 |
Protein deficiency anemia
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| D53.1 |
Other megaloblastic anemias, not elsewhere classified
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|
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| D53.2 |
Scorbutic anemia
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|
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| D53.8 |
Other specified nutritional anemias
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|
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| D53.9 |
Nutritional anemia, unspecified
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|
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| D55.0 |
Anemia due to glucose-6-phosphate dehydrogenase deficiency
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|
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| D55.1 |
Anemia due to other disorders of glutathione metabolism
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|
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| D55.21 |
Anemia due to pyruvate kinase deficiency
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| D55.29 |
Anemia due to other disorders of glycolytic enzymes
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|
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| D55.3 |
Anemia due to disorders of nucleotide metabolism
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|
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| D55.8 |
Other anemias due to enzyme disorders
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|
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| D55.9 |
Anemia due to enzyme disorder, unspecified
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| D56.0 |
Alpha thalassemia
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|
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| D56.1 |
Beta thalassemia
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|
Billable Code | View Code |
| D56.2 |
Delta-beta thalassemia
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| D56.3 |
Thalassemia minor
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| D56.4 |
Hereditary persistence of fetal hemoglobin [HPFH]
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| D56.5 |
Hemoglobin E-beta thalassemia
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|
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| D56.8 |
Other thalassemias
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|
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| D56.9 |
Thalassemia, unspecified
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|
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| D57.00 |
Hb-SS disease with crisis, unspecified
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|
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| D57.01 |
Hb-SS disease with acute chest syndrome
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| D57.02 |
Hb-SS disease with splenic sequestration
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|
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| D57.03 |
Hb-SS disease with cerebral vascular involvement
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|
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| D57.04 |
Hb-SS disease with dactylitis
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|
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| D57.09 |
Hb-SS disease with crisis with other specified complication
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|
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| D57.1 |
Sickle-cell disease without crisis
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|
Billable Code | View Code |
| D57.20 |
Sickle-cell/Hb-C disease without crisis
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|
Billable Code | View Code |
| D57.211 |
Sickle-cell/Hb-C disease with acute chest syndrome
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Billable Code | View Code |
| D57.212 |
Sickle-cell/Hb-C disease with splenic sequestration
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|
Billable Code | View Code |
| D57.213 |
Sickle-cell/Hb-C disease with cerebral vascular involvement
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|
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| D57.214 |
Sickle-cell/Hb-C disease with dactylitis
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Billable Code | View Code |
| D57.218 |
Sickle-cell/Hb-C disease with crisis with oth complication
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|
Billable Code | View Code |
| D57.219 |
Sickle-cell/Hb-C disease with crisis, unspecified
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|
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| D57.3 |
Sickle-cell trait
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|
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| D57.40 |
Sickle-cell thalassemia without crisis
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Billable Code | View Code |
| D57.411 |
Sickle-cell thalassemia, unsp, with acute chest syndrome
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|
Billable Code | View Code |
| D57.412 |
Sickle-cell thalassemia, unsp, with splenic sequestration
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|
Billable Code | View Code |
| D57.413 |
Sickle-cell thalassemia, unsp, with cerebral vascular invl
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|
Billable Code | View Code |
| D57.414 |
Sickle-cell thalassemia, unspecified, with dactylitis
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|
Billable Code | View Code |
| D57.418 |
Sickle-cell thalassemia, unsp, with crisis with oth comp
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|
Billable Code | View Code |
| D57.419 |
Sickle-cell thalassemia, unspecified, with crisis
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|
Billable Code | View Code |
| D57.42 |
Sickle-cell thalassemia beta zero without crisis
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Billable Code | View Code |
| D57.431 |
Sickle-cell thalassemia beta zero with acute chest syndrome
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Billable Code | View Code |
| D57.432 |
Sickle-cell thalassemia beta zero with splenic sequestration
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|
Billable Code | View Code |
| D57.433 |
Sickle-cell thalassemia beta zero with cereb vascular invl
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Billable Code | View Code |
| D57.434 |
Sickle-cell thalassemia beta zero with dactylitis
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Billable Code | View Code |
| D57.438 |
Sickle-cell thalassemia beta zero with crisis with oth comp
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|
Billable Code | View Code |
| D57.439 |
Sickle-cell thalassemia beta zero with crisis, unspecified
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Billable Code | View Code |
| D57.44 |
Sickle-cell thalassemia beta plus without crisis
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Billable Code | View Code |
| D57.451 |
Sickle-cell thalassemia beta plus with acute chest syndrome
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Billable Code | View Code |
| D57.452 |
Sickle-cell thalassemia beta plus with splenic sequestration
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|
Billable Code | View Code |
| D57.453 |
Sickle-cell thalassemia beta plus with cereb vascular invl
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|
Billable Code | View Code |
| D57.454 |
Sickle-cell thalassemia beta plus with dactylitis
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|
Billable Code | View Code |
| D57.458 |
Sickle-cell thalassemia beta plus with crisis with oth comp
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|
Billable Code | View Code |
| D57.459 |
Sickle-cell thalassemia beta plus with crisis, unspecified
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|
Billable Code | View Code |
| D57.80 |
Other sickle-cell disorders without crisis
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|
Billable Code | View Code |
| D57.811 |
Other sickle-cell disorders with acute chest syndrome
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Billable Code | View Code |
| D57.812 |
Other sickle-cell disorders with splenic sequestration
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|
Billable Code | View Code |
| D57.813 |
Other sickle-cell disorders with cerebral vascular invl
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|
Billable Code | View Code |
| D57.814 |
Other sickle-cell disorders with dactylitis
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|
Billable Code | View Code |
| D57.818 |
Other sickle-cell disorders with crisis with oth comp
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|
Billable Code | View Code |
| D57.819 |
Other sickle-cell disorders with crisis, unspecified
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|
Billable Code | View Code |
| D58.0 |
Hereditary spherocytosis
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|
Billable Code | View Code |
| D58.1 |
Hereditary elliptocytosis
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Billable Code | View Code |
| D58.2 |
Other hemoglobinopathies
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|
Billable Code | View Code |
| D58.8 |
Other specified hereditary hemolytic anemias
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|
Billable Code | View Code |
| D58.9 |
Hereditary hemolytic anemia, unspecified
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|
Billable Code | View Code |
| D59.0 |
Drug-induced autoimmune hemolytic anemia
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|
Billable Code | View Code |
| D59.10 |
Autoimmune hemolytic anemia, unspecified
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|
Billable Code | View Code |
| D59.11 |
Warm autoimmune hemolytic anemia
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| D59.12 |
Cold autoimmune hemolytic anemia
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| D59.13 |
Mixed type autoimmune hemolytic anemia
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| D59.19 |
Other autoimmune hemolytic anemia
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|
Billable Code | View Code |
| D59.2 |
Drug-induced nonautoimmune hemolytic anemia
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Billable Code | View Code |
| D59.30 |
Hemolytic-uremic syndrome, unspecified
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Billable Code | View Code |
| D59.31 |
Infection-associated hemolytic-uremic syndrome
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Billable Code | View Code |
| D59.32 |
Hereditary hemolytic-uremic syndrome
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Billable Code | View Code |
| D59.39 |
Other hemolytic-uremic syndrome
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|
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| D59.4 |
Other nonautoimmune hemolytic anemias
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|
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| D59.5 |
Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
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Billable Code | View Code |
| D59.6 |
Hemoglobinuria due to hemolysis from other external causes
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|
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| D59.8 |
Other acquired hemolytic anemias
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|
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| D59.9 |
Acquired hemolytic anemia, unspecified
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|
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| D60.0 |
Chronic acquired pure red cell aplasia
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|
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| D60.1 |
Transient acquired pure red cell aplasia
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|
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Chapter Guidelines
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