Z16.29: Resistance to other single specified antibiotic
Resistance to other single specified antibiotic
Quick Clinical & Billing Summary
What is ICD-10-CM code Z16.29? Z16.29 represents Resistance to other single specified antibiotic. Under official CDC guidelines, this code is billable and specific for claim submission.
Code Hierarchy & Classification
Clinical Guidance & Documentation Standards
Associated Procedures & Medicare RVU Reimbursement
Open RVU Calculator →Typical outpatient and office evaluation procedures frequently billed alongside diagnosis Z16.29:
| CPT/HCPCS | Description | Work RVU | Non-Facility Fee | Facility Fee |
|---|---|---|---|---|
| 99213 | Office/outpatient visit, established patient, 20-29 minutes (Low MDM) | 1.30 | $91.69 | $66.79 |
| 99214 | Office/outpatient visit, established patient, 30-39 minutes (Moderate MDM) | 1.92 | $133.61 | $100.21 |
| 96372 | Therapeutic, prophylactic, or diagnostic injection (subcutaneous/intramuscular) | 0.17 | $18.34 | $12.44 |
CPT Modifier & Billing Rules
Append when a significant, separately identifiable evaluation and management service is provided on the same calendar day as a minor surgical procedure or injection.
Identifies procedures or services not normally reported together but distinct under the clinical circumstances. Use CMS X-modifiers (XE, XS, XP, XU) where required by Medicare.
Frequently Asked Questions about Z16.29
Is Z16.29 a billable ICD-10 code?
Yes, Z16.29 is a valid, billable and specific ICD-10-CM code. It can be reported as a primary or secondary diagnosis on medical claims.
What is the ICD-10 code for Resistance to other single specified antibiotic?
The primary ICD-10-CM code for Resistance to other single specified antibiotic is Z16.29.
What is the effective date of the current Z16.29 code?
The code is active for fiscal year FY2027, effective starting 2026-10-01.
Preparing for the Certified Professional Coder Exam?
Practice ICD-10-CM code identification, sequencing rules, and guideline application with the full CPC Exam Blueprint course.