D57.431: Sickle-cell thalassemia beta zero with acute chest syndrome
Sickle-cell thalassemia beta zero with acute chest syndrome
Quick Clinical & Billing Summary
What is ICD-10-CM code D57.431? D57.431 represents Sickle-cell thalassemia beta zero with acute chest syndrome. Under official CDC guidelines, this code is billable and specific for claim submission.
Code Hierarchy & Classification
Clinical Guidance & Documentation Standards
Associated Procedures & Medicare RVU Reimbursement
Open RVU Calculator →Typical outpatient and office evaluation procedures frequently billed alongside diagnosis D57.431:
| CPT/HCPCS | Description | Work RVU | Non-Facility Fee | Facility Fee |
|---|---|---|---|---|
| 99213 | Office/outpatient visit, established patient, 20-29 minutes (Low MDM) | 1.30 | $91.69 | $66.79 |
| 99214 | Office/outpatient visit, established patient, 30-39 minutes (Moderate MDM) | 1.92 | $133.61 | $100.21 |
| 96372 | Therapeutic, prophylactic, or diagnostic injection (subcutaneous/intramuscular) | 0.17 | $18.34 | $12.44 |
CPT Modifier & Billing Rules
Append when a significant, separately identifiable evaluation and management service is provided on the same calendar day as a minor surgical procedure or injection.
Identifies procedures or services not normally reported together but distinct under the clinical circumstances. Use CMS X-modifiers (XE, XS, XP, XU) where required by Medicare.
Frequently Asked Questions about D57.431
Is D57.431 a billable ICD-10 code?
Yes, D57.431 is a valid, billable and specific ICD-10-CM code. It can be reported as a primary or secondary diagnosis on medical claims.
What is the ICD-10 code for Sickle-cell thalassemia beta zero with acute chest syndrome?
The primary ICD-10-CM code for Sickle-cell thalassemia beta zero with acute chest syndrome is D57.431.
What is the effective date of the current D57.431 code?
The code is active for fiscal year FY2027, effective starting 2026-10-01.
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